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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc975a73b226a58d23003ad0d5fe99d0fb73652a69bb655f035cbed154e04cde' 
  AND token = 'SPPnuVK3t+oqoDCS/+ht2nQyM2uISyni/NBmjs513xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}