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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7f92ca45a88cb7689f6e36e37f8ff606a262e7560146e3638800c20adad67b2' 
  AND token = '1WgP0Sb1NO0OBsWUmlH7BN1B8asYCqlb/kd4IRL0TMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}