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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37defbf2fad015b90cd6e3c46b357255c019de0501a0afb4d4d349f6c22feb6f' 
  AND token = 'U7VkN90MXmSUpEWQrzyYiqk860OwGeZSe9ABk9g28oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}