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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab93c4916a1e8576a2815b19fe0fdf2c6594c84648c3fd8fcb32b60fefa8fa78' 
  AND token = 'TOWyryxZ5OrMffCGJzIVLf46YlAjMcVXQ+qatOTz0jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}