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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cced4be8b4093b935a610b72a1d62a97e6060fd36a25584b6d25ca86091ca52' 
  AND token = 'YOZdUG4qEuQWF7axLjSO/HkuQYxu+jmIrexHWgFQbn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}