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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a5749a3d54c9ff72894aef206059ca1187c97a2a763287c4c14b99ed431db30' 
  AND token = '77VwY5a1C0DXaaWnD2ibBtGE63nvcI+VWQLTvfGgZhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}