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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31ebb0b7811dcfeb759ccf670b6201bae8dfaf50bda3b516274f621e41b0aa10' 
  AND token = 'jE3FT6vkBtDHePcL4s/kD7e+IKcbWFWiCJIfAkeoh0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}