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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '554223c9181c698f6d0788dd1eb04f0addb1e8fbf581c569e58bc3c7f0d6c142' 
  AND token = 'XYyGwYsqmiexD98XD2dNqz5yAIKzkOAo+tAJOj4oEoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}