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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7ff8ec5030cad16f9b63a2ef76c793cd402c27cc01dc14484da66ac5ab1b861' 
  AND token = 'KN/68DTak65mrO2SVwAlYqXwoDw9i8kA5D4tlzTuPwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}