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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ec4060b16a5afe3000a9cfab994c62699ec4dcb6563fbd752f5eb1f4c5daba5' 
  AND token = 'cFREdsZ6+UiqK08Znf9+f17wT/Jh+vttqPWX4jrzWcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}