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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '019e6a0879727ea1dbd2e1bee0dc3d1626bec55e4e9f583c78385b2c12b23c25' 
  AND token = '0I4i70lra18Jsd0b5VHDsuEGBavcw016ua2LhIZT7mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}