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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e87ef9c8ee516cc9dbfa22bbe9fcdde83970f580757526b6c6383a414eaaad' 
  AND token = 'wly1n7XjWcxBkBvcNnR6nfTl5OETcBcW9QG/dXyU3ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}