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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f6b7f7f388479345696ec5bc70233189179451dbacfb54bc6a448bf2f972685' 
  AND token = 'Ostuqp0GwHxA3mni4D5emckVY6LaXkGcGTFDi4+ekVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}