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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e1998047099abf5802980d119f16f8e7e83ea1f07de569c3b09fa11b3587fa3' 
  AND token = 'Mhh91lE/QUIxSAZV2MmPJUKt5XMKBBr9nEnVsUn29ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}