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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '275c9700e0b21aece45685693a69ec6c51da21b60af3731f03f8c6546de890cc' 
  AND token = 'aFQo7RWiyZ1x+dnkdM7bTG90jAOUX1hq+dBIgTE0lT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}