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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7a0dc0d2a29618c88ba765c519b474b096de28668530be41dfe61d4f1c01c85' 
  AND token = 'yMYYR5GakEwOmPvrlfcWY/F78cJ3zMX23KCmyeNgDNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}