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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29dcd2018bbac2fb4ae474ae84fbf5123e349c8651d6f8b05b67f01cddaf0503' 
  AND token = 'gjm4mcQA8G06SlArQeHP+ry4DDTP1bupx1rEAC52Ls0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}