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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4d331633681da6880dfdab2eaf061f4229253e33806ef846a0bb04ede1c932c' 
  AND token = 'ndM9qJKJ5qAdQ+H8pc8dEYwqHbgVZuJ1cYbv2t0wN3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}