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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1555117bc43401c50a223fd010c7955e8f1860f3fad163158733217930d5bf5a' 
  AND token = '+Y13i+qoukDM1eGHfDY8IJfB4bOhPK4zzSl4PUTrMZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}