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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac4b14f2e9d09a66d60ecaae77048dc9a163e7c958c141812fcbbad31107772' 
  AND token = 'm4aEaT2P/c43VcwFOeceG+/SHRM5ceK6/2vhwJeFYdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}