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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '418815be035141149df56e2be7c8c66489718e5f0d2f34e434318988980f8874' 
  AND token = 'Tly+HJ4s4w7SIFKP/KyXIJZZtG2RxaIRzCKP2JNM1ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}