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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3965809d6487f3a3891a604201dfec7faf315bcf68f406ccec36241bbe47257' 
  AND token = 'dH0//ShGGOnlctBtEm/G/N7Otf9rcO+DPJ1D9vJ/zc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}