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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d6a5063c741acb288228f1e52bebe9a7f1578324ebce6752ba4be6b8d3bfc9' 
  AND token = 'H+PPgoNmiYM64XEczCHvRrfwHj7I1udP0uvBuUovHQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}