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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2853c29db9f40bf8d9bb3cf855d0cf1ac20f14a17a370ff522957180a305cbb' 
  AND token = 'BqN7IzDr0ZJe0Skbvh0WOcJArbVth43Ze+CXEFKvLQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}