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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '268a3fc6631e51e328b81a795ab92b9ea29f714530d3bed354aa02638a59e809' 
  AND token = 'kImxqQTSaQAlM+XnKPsbvvtW2+0kxpWA6XP9A1UKxXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}