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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0bca0d655ad3c99c1dce7533ee064558196458f21c95de3b2f873e0c15473e2' 
  AND token = 'V1aW9HBHdpbF0vZOx+D3JBW+Bpl0b7hD57v0ahKK7rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}