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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f40a480a0735e098a2739315a00b64724eff6546e033068e2bd76fd6e5db392f' 
  AND token = 'vwIVA+4dLmGwivOnxc3v+ZBaQAvKsLnxvfLORi6kyaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}