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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '737d4cbe4cfcf6c6f607fe27294e5ffc588f9624423f7c7d7d787c37345d216f' 
  AND token = '+rYoZHxU+66lFxP81pCtv1x0Kau1RcjBr5s4c8vFuw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}