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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f543f7d412eb8ae977a91d23deddd09107c5a1ea665c4e6bd4bf9179875d434' 
  AND token = '/Efv01x9ITXdBtxu7iLFejEK3Y4q8xRMvlIJtrPA1wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}