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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7182f6aab97d90007ed120b0be738d70ad068c6fc89bf44eb66f908ab02d3641' 
  AND token = '9brYEHFb0dnic1kNfzTRy6Fa0WjQNQgBmY1/2DcD/Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}