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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22cf494045c1b4ead2ab5d12c33226bcc146d77c99fe2b0c8b4c4f4d78c5d1b7' 
  AND token = '8CwT6CsYdwj0kL1ivJRoz9Wcjdv+cvBUyHCP2PIMLcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}