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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddc7214a276905953f256c891d6707ee6d85e67ad297cd3c3c9914a3fb1c0ae' 
  AND token = 'yK395DGi2RxV/NVllwXXZhIJI3F6qWKynZfScE6KNOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}