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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b649e84634efa404c8d8c9f4aca2be785b5de53989119a8dffee36a7ac9b1102' 
  AND token = 'MVWh1QhFt2hR1bgLFP5jbxwP3hnwbI+E241gm3THueE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}