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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36a45aedce7385f2ed873ad91894a28317509893098d5e60e369ac63c020e403' 
  AND token = 'IBijQwD/jAFPjROwF2Fbve8EAeO6OwgfbDYD65DYbMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}