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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4530597b60afdeaf3e19b748c8e1d085480fe5084feda648236e5615ca5ca01' 
  AND token = 'adH4wTQEiUhgTz3KYqvgzK+OujTtNP20tAhPds/TjRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}