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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e0d9b190309911f7b5af4ff4a7df9f7425fa96fbc606d4da5803d8a7a13d218' 
  AND token = '8EAiG2B1TYbvLy9C1e+KPBvaglhmPJgYdxSgJ3m6CvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}