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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fc19a30bed26684b51343a11b042c8afe9b20a41df24ec4f20db40e53d0b01' 
  AND token = 'Gw9qXQN+9u7NvTSYw02wRP55dnyo8ZHEsBW58MzRQ1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}