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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2d3a75e7c36b45ae662843a41db542bdcb0bb87d022ac5044f6851b8c512f7b' 
  AND token = 't+u9jKu+dgnHqa0I520taLahzRtjAtTg09lqFh+Izi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}