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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f59902ced945df53248d11b8d1ecd44d9c7d8c56a0137963d2b1a336b7eae40a' 
  AND token = 'IBJ5MH+WkRcWn04bQxq4Hb6pjDGs9+uMiQ6qxQirvzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}