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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37490004482b236e19b56e0b4a78d294c3b15e3899d5e32e3fac4cc8534e3a7b' 
  AND token = 'J+TG13CGoyq3HtuA1F2VACVMaWs9KnnlNa3+ZxbZdG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}