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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d880031e4e06edc898c74df78b5c564344005b76f613eb85de1aef65b8c058' 
  AND token = 'bCFW1SWKNj0mD2uuHV8T+9R5qTPWG0IZIimVl46tsBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}