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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18734762162909c2d2602f8834f69ca25cb540fd31e1508aef7a1748bf1d02cb' 
  AND token = 'wbNOHwDpKMw/aC7VtkN0hLNH6+Rodf7JOLWu71XwZT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}