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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a3927d6cd04582e97d6c03a8b275261ff057f637e05cc5e47e41796a5222399' 
  AND token = '9YjrCVvlvTkqx0A3esjCfoJ+XXM1bvTC13de9PnECUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}