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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4256c3c948effe0c6f5a51ba4526ff3bc9d96e7c78c5567e2d1c433cd49884c2' 
  AND token = 'EgVWDJW/wd/KPRWNbEy3CRssDv0jf6mrHzfrM/3bu1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}