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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0a2cabfe115316e0d0e05df6fb79a61ca2b02bffa0298203b5b6825110087d2' 
  AND token = 'xKHNoUd28R9G7sDEWRaGJuCt1njNLvS8G1fRVuYCO5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}