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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab92973aabefe0b465d4406ca5c11e39f7bdcc4da24ceb9467c7241e96e7008a' 
  AND token = 'H3Ff1Yhf3LHD4TeiLPyRWbRSdm740WwPTLYM3NmDsY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}