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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49eea3fe132a2778c1ac4dcaf900b2936e9c9262edc4d01e8a0fc1cc8bb84f8' 
  AND token = '6Kn69e6hF+m4AhiPAhRDD8Zxrhm0cSxiWqlxTkGBaEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}