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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6478fc9faa53fd56633e66e380936efd8f027a971873d4b1792b567fa3b8fc48' 
  AND token = 'eq1NDOyr+VOZUjD5y2RU/Wkf6Fk6IvK5dlgkBneyrzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}