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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1442c4a166ad85ccdf03f905f818a11766af2a6ab7a0eab18722da6549d9ba00' 
  AND token = '06hpcos773oI5t844+yxul1vR6dKaJv11ExQzImr+QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}