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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243eb965ce29260003baa0542b45f24a34edfadaa9a91d982b9432f28c190ee5' 
  AND token = 'YKi1v3PO5Tad7Q7Mj0RI5dYWsSSiUGdr4Jpcgo6MqTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}